Neutrophil-to-lymphocyte ratio as a prognostic predictor in adrenocortical carcinoma: a retrospective cohort study stratified by cortisol secretion status
Preoperative NLR >3.9 may serve as a simple and accessible prognostic marker for DSS in Chinese patients with ACC. Its predictive value is influenced by both tumor-induced inflammation and cortisol secretion, highlighting its utility in risk stratification beyond traditional factors.
Authors
- Mengyi Li (ORCID: https://orcid.org/0009-0004-3255-2077)
- Beiyan Liu
- Bingyin Shi
- Qiang Wei (ORCID: https://orcid.org/0000-0003-0535-8506)
- Dapeng Wu (ORCID: https://orcid.org/0000-0001-9446-8365)
- Hui Guo (ORCID: https://orcid.org/0000-0001-8442-6487)
- Xuna Kou
- Jin Shang
- Jiaojiao Zhang
- Zhiqiu Sun
- Axing Li
- Tongxin Zhang
- Ruiqing Dong
Institutions
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
- Jilin Academy of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Translational Cancer Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.21037/tcr-2025-aw-2335
- Primary Topic
- Adrenal and Paraganglionic Tumors
- Type
- article
- Field-Weighted Citation Impact
- 0.00