Creativity and transition to bipolar disorder: a prospective analysis from the early-bipolife study

High BD risk was associated with higher CAQ scores at BL, suggesting heightened creativity may precede transition. Prospective analyses over two years did not confirm this association, likely due to the small number of transitions. Nonetheless, cross-sectional differences and group comparisons suggest that individuals with both high BD risk and high creativity, particularly real-world accomplishments captured by the CAQ, may show an increased likelihood of transition. These preliminary findings warrant replication in larger, longer-term studies. Importantly, creativity should not be pathologized but considered both as a resource and as a potential modifier of risk trajectories.

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Publication Details

Journal
International Journal of Bipolar Disorders
Published
2025-12-31
DOI
https://doi.org/10.1186/s40345-025-00406-6
Primary Topic
Bipolar Disorder and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Creativity and transition to bipolar disorder: a prospective analysis from the early-bipolife study

Pavol Mikoláš, Eva Burkhardt, M Lambert, Felix Bermpohl et al.
International Journal of Bipolar Disorders
Bipolar Disorder and Treatment
article

Creativity and transition to bipolar disorder: a prospective analysis from the early-bipolife study

Pavol Mikoláš, Eva Burkhardt, M Lambert, Felix Bermpohl, Christina Berndt, T. Kircher, Philipp Ritter, Julia Martini, Silke Matura, Birgit Maicher, Matthias Bauer, Eva Mennigen, Irina Falkenberg, Andrea Pfennig, Thomas Stamm, Sarina Hadji, Cathrin Sauer, Georg Juckel, Elisabeth Michaelis, Kyra Bröckel-Bundt, Sarah Kittel-Schneider, Paolo Fusar-Poli, Udo Dannlowski, Andreas Reif, Andreas J. Fallgatter, Karolina Leopold, Andreas Jansen, Christoph U. Correll, Andreas Bechdolf, Seza Krüger-Özgürdal
article en

Abstract

High BD risk was associated with higher CAQ scores at BL, suggesting heightened creativity may precede transition. Prospective analyses over two years did not confirm this association, likely due to the small number of transitions. Nonetheless, cross-sectional differences and group comparisons suggest that individuals with both high BD risk and high creativity, particularly real-world accomplishments captured by the CAQ, may show an increased likelihood of transition. These preliminary findings warrant replication in larger, longer-term studies. Importantly, creativity should not be pathologized but considered both as a resource and as a potential modifier of risk trajectories.

International Journal of Bipolar DisordersVol. 14(1)
Goethe University Frankfurt (DE), Northwell Health (US), Universität Hamburg (DE), Philipps University of Marburg (DE), King's College London (GB), University of Münster (DE), University of Pavia (IT), University College Cork (IE), Humboldt-Universität zu Berlin (DE), Psychiatry Baselland (CH), Donald & Barbara Zucker School of Medicine at Hofstra/Northwell (US), University Medical Center Hamburg-Eppendorf (DE), St. Hedwig-Krankenhaus (DE), King's College School (GB), University Children's Hospital Tübingen (DE), Universitätsklinikum Würzburg (DE), University Hospital Frankfurt (DE), Medizinische Hochschule Brandenburg Theodor Fontane (DE), LWL-Universitätsklinikum Bochum (DE), German Center for Diabetes Research (DE), University Hospital Carl Gustav Carus (DE), Zucker Hillside Hospital (US), Charité - Universitätsmedizin Berlin (DE), University of Tübingen (DE), Ruhr University Bochum (DE)
Openalex Percentile: Top 31%
Bipolar Disorder and Treatment
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