Correlation of EZH2 expression and response to chemoradiation in patients with locally advanced inoperable oral cavity and oropharyngeal squamous cell cancers

The study indicates that EZH2 can be a valuable predictive marker in HNC. Anti-EZH2 therapy should be explored to improve the treatment outcomes in patients with high expression of EZH2.

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Publication Details

Journal
Journal of Cancer Research and Therapeutics
Published
2025-10-01
DOI
https://doi.org/10.4103/jcrt.jcrt_1467_25
Primary Topic
Epigenetics and DNA Methylation
Type
article
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article

Correlation of EZH2 expression and response to chemoradiation in patients with locally advanced inoperable oral cavity and oropharyngeal squamous cell cancers

Pradipta Kumar Parida, Arnab Sarkar, Anupam Muraleedharan, D. Muduly et al.
Journal of Cancer Research and Therapeutics
Epigenetics and DNA Methylation
article

Correlation of EZH2 expression and response to chemoradiation in patients with locally advanced inoperable oral cavity and oropharyngeal squamous cell cancers

Pradipta Kumar Parida, Arnab Sarkar, Anupam Muraleedharan, D. Muduly, Mathan Kumar Ramasubbu, Deepak Das, Ankur Mahajan, Amit Kumar Adhya, Saroj Kumar Das Majumdar, Shaha Sheik Abdulla, Phanindra Kumar Swain, Nehla Haroon, Sandip Kumar Barik, S. K. Soel Ahmed, Priyanka Mukherjee, Dillip Kumar Parida
article en

Abstract

The study indicates that EZH2 can be a valuable predictive marker in HNC. Anti-EZH2 therapy should be explored to improve the treatment outcomes in patients with high expression of EZH2.

Journal of Cancer Research and TherapeuticsVol. 21(7)
Amrita Institute of Medical Sciences and Research Centre (IN), Tata Memorial Hospital (IN), All India Institute of Medical Sciences Bhubaneswar (IN), Nference (India) (IN)
No poverty
Openalex Percentile: Top 35%
Epigenetics and DNA Methylation
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