β-Selective Heck reactions of unprotected allylamines driven by surface charge of <i>in situ</i> -formed Pd nanoparticles
Arylation of allylamines typically favors addition of the new aryl at the γ-position via an insertion mechanism. However, by using a relatively electronically neutral reduced metal nanoparticle, the selectivity of this reaction can be switched to β.
Authors
- Olutayo Nathanael Farinde (ORCID: https://orcid.org/0000-0002-1287-0017)
- Vinod G. Landge (ORCID: https://orcid.org/0000-0003-1241-4561)
- Michael C. Young (ORCID: https://orcid.org/0000-0002-3256-5562)
- Radha Kondapalli
- Abigail M. Gohmann
- Allison V. Gottshall
- Oreoluwa Ayomide Adeyemo
- Satheesh Vanaparthi
- Kendra Kumar Shrestha
- G. Brant Hunt
- Justin Maxwell
Institutions
- University of Toledo (US)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-12-31
- DOI
- https://doi.org/10.1039/d5qo01463h
- Primary Topic
- Catalytic Cross-Coupling Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00