Association between <i>ABCG2</i> polymorphisms and allopurinol response in gout patients: a systematic review and meta-analysis

The findings suggest that <i>ABCG2</i> rs2231142 influences allopurinol response. These results underscore the potential of rs2231142 as a predictive genetic marker for allopurinol efficacy and may inform the development of pharmacogenomic guidelines for gout management.This systematic review and meta-analysis was not registered in any protocol registry.

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Publication Details

Journal
Pharmacogenomics
Published
2025-12-12
DOI
https://doi.org/10.1080/14622416.2025.2609364
Citations
1
Primary Topic
Gout, Hyperuricemia, Uric Acid
Type
article
Field-Weighted Citation Impact
1.43
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article

Association between ABCG2 polymorphisms and allopurinol response in gout patients: a systematic review and meta-analysis

Xin Yee Low, Muhammad Danish Badrul Hisham, L. K. Teh, Jia Wen Lee
1 citations
Pharmacogenomics
Gout, Hyperuricemia, Uric Acid
1.43
article

Association between ABCG2 polymorphisms and allopurinol response in gout patients: a systematic review and meta-analysis

Xin Yee Low, Muhammad Danish Badrul Hisham, L. K. Teh, Jia Wen Lee
article en
1 citations

Abstract

The findings suggest that <i>ABCG2</i> rs2231142 influences allopurinol response. These results underscore the potential of rs2231142 as a predictive genetic marker for allopurinol efficacy and may inform the development of pharmacogenomic guidelines for gout management.This systematic review and meta-analysis was not registered in any protocol registry.

PharmacogenomicsVol. 26(17-18)
Mahsa University (MY), Universiti Teknologi MARA (MY)
Good health and well-being
Openalex Percentile: Top 13%
Gout, Hyperuricemia, Uric Acid
1.43
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