RIC-specific cytoprotective profile mediated by microglia in a mouse model of acute ischaemic stroke
These findings reveal sex-specific efficacy of RIC, with mechanistic insights obtained in male animals suggesting a dual mode of action via modulation of microglial function and promotion of endogenous neurorepair pathways.
Authors
- Glòria Arqué (ORCID: https://orcid.org/0000-0002-8039-3726)
- Coral Torres-Querol (ORCID: https://orcid.org/0000-0002-2513-7076)
- Francisco Purroy
Institutions
- Universitat de Lleida (ES)
- Hospital Universitari Arnau de Vilanova (ES)
- Instituto de Investigación Biomédica de Lleida (ES)
Publication Details
- Journal
- Stroke and Vascular Neurology
- Published
- 2025-12-31
- DOI
- https://doi.org/10.1136/svn-2025-004465
- Primary Topic
- Cardiac Ischemia and Reperfusion
- Type
- article
- Field-Weighted Citation Impact
- 0.00