ZBP1 aggravates acute lung injury in mice by promoting the macrophage inflammatory phenotype

miR-1298-5p downregulates ZBP1 expression and inhibits NF-κB signaling pathway-mediated mitochondrial dysfunction, thereby inhibiting the M1 polarization of macrophages and the progression of ALI.

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Publication Details

Journal
Immunobiology
Published
2025-12-31
DOI
https://doi.org/10.1016/j.imbio.2025.153154
Primary Topic
Connective tissue disorders research
Type
article
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article

ZBP1 aggravates acute lung injury in mice by promoting the macrophage inflammatory phenotype

Yuan Liao, Dai Qiu, Yongze Liu, Jiawu Yang et al.
Immunobiology
Connective tissue disorders research
article

ZBP1 aggravates acute lung injury in mice by promoting the macrophage inflammatory phenotype

Yuan Liao, Dai Qiu, Yongze Liu, Jiawu Yang, Xiaoliang Du, Hong Li, Feng Li
article en

Abstract

miR-1298-5p downregulates ZBP1 expression and inhibits NF-κB signaling pathway-mediated mitochondrial dysfunction, thereby inhibiting the M1 polarization of macrophages and the progression of ALI.

ImmunobiologyVol. 231(1)
Kunming Medical University (CN), Kunming Children's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 24%
Connective tissue disorders research
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