Hepatocyte-Derived Exosomes Reduce Hepatic Ischemia-Reperfusion (IR) Injury by Inhibiting Complement Activation
Our findings highlight the ability of hepatocyte-derived exosomes to mitigate hepatic IRI by inhibiting complement activation. These results reveal a novel role for exosomes in blocking complement activation, suggesting a potential new therapeutic avenue for preventing hepatic IRI.
Authors
- Y. Wang
- Bin null Deng
- Wei null Dong
- Junfei null Jin
- Zhixiong null Pan
- Zhi null Yang
- Tian null Sun
Institutions
- Guilin Medical University (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-12-18
- DOI
- https://doi.org/10.31083/fbl46946
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science and Technology Department of Guangxi Zhuang Autonomous
- Guilin Medical University