Development and In Vivo Evaluation of a Novel Bioabsorbable Polylactic Acid Middle Ear Ventilation Tube
The developed PLA middle-ear ventilation tube represents a highly promising alternative to conventional non-absorbable tubes. It demonstrates excellent biocompatibility, preserves auditory function, and exhibits a controlled degradation profile. This preclinical study provides strong support for further investigation and subsequent clinical trials to validate its safety and efficacy in human patients.
Authors
- Haigang Wu (ORCID: https://orcid.org/0000-0002-8565-960X)
- Chi-Chieh Chang (ORCID: https://orcid.org/0000-0002-0783-2868)
- Ping-Tun Teng
- Chueh‐Hung Wu (ORCID: https://orcid.org/0000-0002-3979-3541)
- Wu Chen-Chi
- Yen-Hui Chan
- Tien-Chen Liu
- Ying-Chang Lu
- Chiung-Ju Lin
Institutions
- Powertech Technology (Taiwan) (TW)
- National Taiwan University Hospital (TW)
Publication Details
- Journal
- Journal of Functional Biomaterials
- Published
- 2025-12-30
- DOI
- https://doi.org/10.3390/jfb17010025
- Primary Topic
- Ear Surgery and Otitis Media
- Type
- article
- Field-Weighted Citation Impact
- 0.00