Advance biocatalyst for the green conversion of 5-hydroxymethylfurfural to a biopolymer precursor 2,5-furandicarboxylic acid
The identified and characterized PSPO was found to have a potential for the accelerated enzymatic oxidation of HMF to FDCA. Through molecular dynamic (MD) simulations of the catalytic pathway and enzyme mechanisms, alongside assessing the impact of substrate concentration, PSPO turns out to be a potential candidate for enhancing reaction efficiency and maximizing yield.
Authors
- Rishu Dhiman
- Sudesh Kumar Yadav (ORCID: https://orcid.org/0000-0002-3215-0308)
- Divya Mittal (ORCID: https://orcid.org/0000-0002-8183-284X)
- Rituraj Purohit
- Ashutosh Kumar
- Lata Pawar
- Pramod Kumar
Institutions
- Indian Institute of Science Education and Research Mohali (IN)
- Institute of Himalayan Bioresource Technology (IN)
- BRIC-National Agri-Food and Biomanufacturing Institute (IN)
Publication Details
- Journal
- Biotechnology for Biofuels and Bioproducts
- Published
- 2025-12-31
- DOI
- https://doi.org/10.1186/s13068-025-02705-7
- Primary Topic
- Catalysis for Biomass Conversion
- Type
- article
- Field-Weighted Citation Impact
- 0.00