Identification of prognostic genes associated with mitochondria and macrophage polarization in prostate adenocarcinoma based on transcriptome and Mendelian randomization analysis

This study identified seven prognostic genes and provided a new theoretical basis for exploring immune defense mechanisms and targeted therapeutic drugs in PRAD.

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Publication Details

Journal
Discover Oncology
Published
2025-12-31
DOI
https://doi.org/10.1007/s12672-025-03858-5
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Identification of prognostic genes associated with mitochondria and macrophage polarization in prostate adenocarcinoma based on transcriptome and Mendelian randomization analysis

Hao Bian, Zhen Wei, Guanfeng Wang, Jiancheng Cao et al.
Discover Oncology
Ferroptosis and cancer prognosis
article

Identification of prognostic genes associated with mitochondria and macrophage polarization in prostate adenocarcinoma based on transcriptome and Mendelian randomization analysis

Hao Bian, Zhen Wei, Guanfeng Wang, Jiancheng Cao, Chengjun Zhao, Li Heng
article en

Abstract

This study identified seven prognostic genes and provided a new theoretical basis for exploring immune defense mechanisms and targeted therapeutic drugs in PRAD.

Discover OncologyVol. 17(1)
Kailuan General Hospital (CN), Hanzhong People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 27%
Ferroptosis and cancer prognosis
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