Acupuncture Modulates NMDAR-PP1/Calpain1-KCC2 Pathway to Ameliorate Spinal Hyperexcitability and Spastic Hemiplegia Induced by Ischemic Stroke
Acupuncture modulated the NMDAR-PP1/Calpain1-KCC2 pathway in the spinal cord to suppress neuronal hyperexcitability, thereby relieving spasticity and promoting motor function in rats with PSSH.
Authors
- Jia Wen (ORCID: https://orcid.org/0009-0009-8216-6883)
- Jia-Ling null He
- Meng-Yu null Chen
- Jing-Yun null Xiu
- Yu-Xin null Zhuang
- Liang-Xiao null Ma
- Ling-Hui null Ma
Institutions
- Beijing University of Chinese Medicine (CN)
- State Administration of Traditional Chinese Medicine of the People's Republic of China (CN)
Publication Details
- Journal
- Journal of Integrative Neuroscience
- Published
- 2025-12-26
- DOI
- https://doi.org/10.31083/jin46980
- Primary Topic
- Botulinum Toxin and Related Neurological Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00