Differential Impact of Recruited and Resident Macrophages on Hypoxia-Induced Pulmonary Hypertension
The differential roles of pulmonary resMФs and recMФs in pulmonary vascular remodeling highlight novel therapeutic targets for pulmonary arterial hypertension treatment, specifically through inhibition of <i>Hic1</i> and <i>Prrx2</i> in macrophages.
Authors
- Jiong-Wei Wang
- Ronglu Du (ORCID: https://orcid.org/0000-0001-9327-7073)
- Xia Tang (ORCID: https://orcid.org/0000-0002-5646-5558)
- Danyang Tian (ORCID: https://orcid.org/0000-0002-4553-0115)
- Vladimír Kořínek (ORCID: https://orcid.org/0000-0002-9777-4664)
- Dandan Huang (ORCID: https://orcid.org/0009-0002-3503-5855)
- Yujuan Zhuo
- Xin Cao
- Yuanyuan Cheng
- Shumin Guo
- Yong Qi
- Yan Zhao
- Qian Liu
- Ying Yu
- Yongle Huang
- Cheng Dong
- Ting Pan
- Xinxin Shi
- Titi Qiang
- Yujun Shen
- Bin Zhou
- Xiaojie Yan
Institutions
- Hebei Medical University (CN)
- National University of Singapore (SG)
- Sichuan University (CN)
- Ministry of Education (KR)
- Center for Excellence in Molecular Cell Science (CN)
- Institute of Molecular Genetics (RU)
- Henan Provincial People's Hospital (CN)
- Ministry of Education (KN)
- University of Hong Kong (HK)
Publication Details
- Journal
- Circulation Research
- Published
- 2025-12-31
- DOI
- https://doi.org/10.1161/circresaha.125.326472
- Citations
- 1
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.52