Genotype-specific Response to 144-week Entecavir Therapy for HBeAg-positive Chronic Hepatitis B with a Particular Focus on Histological Improvement: A Prospective Study

HBV genotype B demonstrates superior histological responses to ETV therapy compared with genotype C, supporting the clinical value of HBV genotyping for personalized CHB management. These findings highlight the importance of considering viral genotype when evaluating treatment outcomes.

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Publication Details

Journal
Journal of Clinical and Translational Hepatology
Published
2025-12-31
DOI
https://doi.org/10.14218/jcth.2025.00533
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Genotype-specific Response to 144-week Entecavir Therapy for HBeAg-positive Chronic Hepatitis B with a Particular Focus on Histological Improvement: A Prospective Study

Guoxin Huang, Lexin Liu, Zehui Wei, Shanshan Lin et al.
Journal of Clinical and Translational Hepatology
Hepatitis B Virus Studies
article

Genotype-specific Response to 144-week Entecavir Therapy for HBeAg-positive Chronic Hepatitis B with a Particular Focus on Histological Improvement: A Prospective Study

Guoxin Huang, Lexin Liu, Zehui Wei, Shanshan Lin, Qiumiao Xu
article en

Abstract

HBV genotype B demonstrates superior histological responses to ETV therapy compared with genotype C, supporting the clinical value of HBV genotyping for personalized CHB management. These findings highlight the importance of considering viral genotype when evaluating treatment outcomes.

Journal of Clinical and Translational HepatologyVol. 000(000)
Sun Yat-sen University (CN), Sixth Affiliated Hospital of Sun Yat-sen University (CN), Guangdong Provincial Hospital of Traditional Chinese Medicine (CN), Shenzhen Pingle Orthopedic Hospital (CN)
Good health and well-being
Openalex Percentile: Top 29%
Hepatitis B Virus Studies
DOIOpen Access PDFOpenAlex
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