A Case of Reverse Takotsubo in a Patient with Seizure Disorder

Abstract First described in Japan in the 1990s, Takotsubo cardiomyopathy (TTC) is an acute but reversible left ventricular dysfunction presenting as apical ballooning or focal wall motion abnormalities. It is usually triggered by emotional, physical, or combined triggers. Multiple variants of Takotsubo syndrome have been reported, including Reverse TTC (rTTC), which is a variant characterized by basal akinesis/hypokinesis with apical hyperkinesia. Takotsubo syndrome accounts for ≈ 2%–3% of all patients and 5%–6% of female patients presenting with acute coronary syndrome. The condition can occur in any age group. Younger patients are more likely to be male or have atypical Takotsubo. We present the case of a 39-year-old male patient who had rTTC and offer a review of the literature regarding the disease, as its recognition improves the assessment of patient prognosis and management.