Drug‐Induced Liver Injury Associated With Moxifloxacin: A Pharmacovigilance Analysis of the FDA Adverse Event Reporting System and a Real‐World Retrospective Study

Despite widespread clinical use, moxifloxacin's safety profile requires systematic evaluation. Clinicians should monitor liver function and integrate risk stratification, including albumin levels, gender and concomitant medications into prescribing practices. Elucidating DILI mechanisms and high-risk populations may optimize therapeutic decision-making and patient safety.

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Publication Details

Journal
Basic & Clinical Pharmacology & Toxicology
Published
2025-12-31
DOI
https://doi.org/10.1111/bcpt.70187
Primary Topic
Drug-Induced Hepatotoxicity and Protection
Type
article
Field-Weighted Citation Impact
0.00
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article

Drug‐Induced Liver Injury Associated With Moxifloxacin: A Pharmacovigilance Analysis of the FDA Adverse Event Reporting System and a Real‐World Retrospective Study

Chunzi Li, Yanqing Song, Huan Gao, Xiaoyue Liu
Basic & Clinical Pharmacology & Toxicology
Drug-Induced Hepatotoxicity and Protection
article

Drug‐Induced Liver Injury Associated With Moxifloxacin: A Pharmacovigilance Analysis of the FDA Adverse Event Reporting System and a Real‐World Retrospective Study

Chunzi Li, Yanqing Song, Huan Gao, Xiaoyue Liu
article en

Abstract

Despite widespread clinical use, moxifloxacin's safety profile requires systematic evaluation. Clinicians should monitor liver function and integrate risk stratification, including albumin levels, gender and concomitant medications into prescribing practices. Elucidating DILI mechanisms and high-risk populations may optimize therapeutic decision-making and patient safety.

Basic & Clinical Pharmacology & ToxicologyVol. 138(2)
Jilin University (CN), First Hospital of Jilin University (CN), Jilin Medical University (CN)
Openalex Percentile: Top 29%
Drug-Induced Hepatotoxicity and Protection
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Drug‐Induced Liver Injury Associated With Moxifloxacin: A Pharmacovigilance Analysis of the FDA Adverse Event Reporting System and a Real‐World Retrospective Study — Chunzi Li, Yanqing Song, et al. · Basic & Clinical Pharmacology & Toxicology (2025) | TGRS Research Map | TGRS