Prefrontal <scp>TRPM8</scp> Receptor Modulates Epileptic Seizures via <scp>PKA</scp> / <scp>CREB</scp> Signaling Pathway in Mice
Prefrontal TRPM8 receptor plays a vital role in PTZ-induced acute seizures through the PKA/CREB pathway, which provides a potential target for the treatment of seizures.
Authors
- Zhi Long Zhang (ORCID: https://orcid.org/0000-0003-3594-6739)
- Yihan Jiang
- Jia‐Zhan Huang
- Yao Guo
- Gui‐Feng Lu
- Fei Geng
- Ze‐Yu Lin
Institutions
- Shantou University (CN)
- Shantou University Medical College (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2025-12-31
- DOI
- https://doi.org/10.1002/cns.70709
- Primary Topic
- Ion Channels and Receptors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Shantou University Medical College
- Basic and Applied Basic Research Foundation of Guangdong Province