Triglyceride glucose index and atherogenic index of plasma predict rapid kidney function decline in cardiovascular–kidney–metabolic syndrome: the first longitudinal evidence from CHARLS

Our findings demonstrate the utility of the TyG index and AIP as effective biomarkers for stratifying the risk of RKFD in the clinical management of CKM syndrome. Furthermore, uric acid plays a significant partial mediating role in this relationship.

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Publication Details

Journal
European journal of medical research
Published
2025-12-31
DOI
https://doi.org/10.1186/s40001-025-03751-5
Primary Topic
Chronic Kidney Disease and Diabetes
Type
article
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article

Triglyceride glucose index and atherogenic index of plasma predict rapid kidney function decline in cardiovascular–kidney–metabolic syndrome: the first longitudinal evidence from CHARLS

Xiaohua PEI, Yifan Wang, Yan Wang, Xueqi Chen et al.
European journal of medical research
Chronic Kidney Disease and Diabetes
article

Triglyceride glucose index and atherogenic index of plasma predict rapid kidney function decline in cardiovascular–kidney–metabolic syndrome: the first longitudinal evidence from CHARLS

Xiaohua PEI, Yifan Wang, Yan Wang, Xueqi Chen, Mengying Dong, Weihong Zhao, Yao Ma, Xueyi Xia, Yun Bo
article en

Abstract

Our findings demonstrate the utility of the TyG index and AIP as effective biomarkers for stratifying the risk of RKFD in the clinical management of CKM syndrome. Furthermore, uric acid plays a significant partial mediating role in this relationship.

European journal of medical researchVol. 31(1)
Nanjing Medical University (CN)
Good health and well-being
Openalex Percentile: Top 30%
Chronic Kidney Disease and Diabetes
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