Human epidermal growth factor receptor 2 and androgen receptor expression in invasive breast carcinoma of no special type with medullary pattern

Our findings suggest that BCNST-MP tumors are rarely larger than 5 cm and are frequently lymph node-negative. Most patients were negative for ER, PR, AR, and HER2. Notably, HER2-low expression was observed in approximately 30% of cases, suggesting therapeutic implications.

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Publication Details

Journal
Journal of Cancer Research and Therapeutics
Published
2025-12-01
DOI
https://doi.org/10.4103/jcrt.jcrt_455_25
Primary Topic
Breast Cancer Treatment Studies
Type
article
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article

Human epidermal growth factor receptor 2 and androgen receptor expression in invasive breast carcinoma of no special type with medullary pattern

Jun Shao, Yaojun Feng, Tiejun Wang, Liting Jin et al.
Journal of Cancer Research and Therapeutics
Breast Cancer Treatment Studies
article

Human epidermal growth factor receptor 2 and androgen receptor expression in invasive breast carcinoma of no special type with medullary pattern

Jun Shao, Yaojun Feng, Tiejun Wang, Liting Jin, Manxiu Li
article en

Abstract

Our findings suggest that BCNST-MP tumors are rarely larger than 5 cm and are frequently lymph node-negative. Most patients were negative for ER, PR, AR, and HER2. Notably, HER2-low expression was observed in approximately 30% of cases, suggesting therapeutic implications.

Journal of Cancer Research and TherapeuticsVol. 21(6)
Hubei Cancer Hospital (CN), Huazhong University of Science and Technology (CN)
Openalex Percentile: Top 32%
Breast Cancer Treatment Studies
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Human epidermal growth factor receptor 2 and androgen receptor expression in invasive breast carcinoma of no special type with medullary pattern — Jun Shao, Yaojun Feng, et al. · Journal of Cancer Research and Therapeutics (2025) | TGRS Research Map | TGRS