Spontaneous bilateral chylothorax in a patient with epilepsy

This case report discusses a woman in her 30s presenting with an acute, rapidly progressive left anterior cervical swelling. While the neck swelling improved spontaneously, the patient subsequently developed large bilateral pleural effusions with respiratory failure requiring ventilatory support in the high dependency unit. Therapeutic thoracocentesis yielded chylous pleural fluid bilaterally. The respiratory failure subsequently improved and the patient was discharged home. This was an atypical presentation of chylothorax with no history of malignancy, atypical infection or apparent blunt trauma to the thoracic cage. The presence of bilateral chylothoraces suggested a multilevel thoracic duct injury. A significant tonic-clonic epileptic seizure, 6 days prior, is hypothesised as the potential underlying cause, which has not previously been reported in the literature.

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Publication Details

Journal
BMJ Case Reports
Published
2025-12-01
DOI
https://doi.org/10.1136/bcr-2025-270661
Primary Topic
Lymphatic Disorders and Treatments
Type
article
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article

Spontaneous bilateral chylothorax in a patient with epilepsy

Chloe Lawrence, Simon Wharton, Christopher Huntley, Osama Abulaban et al.
BMJ Case Reports
Lymphatic Disorders and Treatments
article

Spontaneous bilateral chylothorax in a patient with epilepsy

Chloe Lawrence, Simon Wharton, Christopher Huntley, Osama Abulaban, Callum James Riley, Angela Holden, Shayan Lihony
article en

Abstract

This case report discusses a woman in her 30s presenting with an acute, rapidly progressive left anterior cervical swelling. While the neck swelling improved spontaneously, the patient subsequently developed large bilateral pleural effusions with respiratory failure requiring ventilatory support in the high dependency unit. Therapeutic thoracocentesis yielded chylous pleural fluid bilaterally. The respiratory failure subsequently improved and the patient was discharged home. This was an atypical presentation of chylothorax with no history of malignancy, atypical infection or apparent blunt trauma to the thoracic cage. The presence of bilateral chylothoraces suggested a multilevel thoracic duct injury. A significant tonic-clonic epileptic seizure, 6 days prior, is hypothesised as the potential underlying cause, which has not previously been reported in the literature.

BMJ Case ReportsVol. 18(12)
Birmingham City University (GB), University Hospitals Birmingham NHS Foundation Trust (GB), University College Birmingham (GB), University of Birmingham (GB)
Good health and well-being
Openalex Percentile: Top 25%
Lymphatic Disorders and Treatments
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Spontaneous bilateral chylothorax in a patient with epilepsy — Chloe Lawrence, Simon Wharton, et al. · BMJ Case Reports (2025) | TGRS Research Map | TGRS