Front Cover: Targeted Nanocomplex Delivery for Protecting Vascular Integrity and Enhancing Anticancer Effects in Hepatocellular Carcinoma (Small Sci. 1/2026)
Nanocarriers In article number 2400616, Seung-Woo Cho, Wonhwa Lee, Jae-Young Lee, Hong Nam Kim, and co-workers developed hepatocarcinoma-targeted nanocarriers encapsulating anti-tumor drugs to enhance delivery to solid tumors while minimizing vascular inflammation-related side effects. Across animal models and liver-tumor-on-a-chip platforms, these nanocarriers achieved markedly improved cellular uptake, stronger anti-tumor responses, and reduced vascular injury, underscoring their potential as an efficient and safe nanomedicine platform for liver cancer therapy.
Authors
- Hee Ho Park (ORCID: https://orcid.org/0000-0003-1498-5624)
- S. Kim
- June Hong Ahn (ORCID: https://orcid.org/0000-0001-7104-8325)
- H Kim (ORCID: https://orcid.org/0000-0001-7374-0892)
- Jae‐Young Lee (ORCID: https://orcid.org/0000-0002-2430-6130)
- Taeeun Kwon (ORCID: https://orcid.org/0009-0007-7661-485X)
- Han Sol Lee
- Seung‐Woo Cho (ORCID: https://orcid.org/0000-0001-8058-332X)
- Hong Nam Kim
- So‐Yeol Yoo
- Donghyuk Seo
Institutions
- Seoul National University (KR)
- Chosun University (KR)
- Yonsei University (KR)
- Chungnam National University (KR)
- Korea University (KR)
- Korea Institute of Brain Science (KR)
- Korean Association Of Science and Technology Studies (KR)
- Bio-Medical Science (South Korea) (KR)
- Yeungnam University Medical Center (KR)
- Korea Institute of Science and Technology (KR)
- Sungkyunkwan University (KR)
- Korea University of Science and Technology (KR)
Publication Details
- Journal
- Small Science
- Published
- 2025-12-31
- DOI
- https://doi.org/10.1002/smsc.70188
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00