Intestinal epitheliotropic T-cell lymphoma in a dog: a case report

A 13-year-old neutered male Shih Tzu presented with diffuse intestinal thickening extending from the lower part of the duodenum to the middle part of the jejunum. A portion of the jejunum was biopsied and submitted for histopathological diagnosis. Microscopically, the villi of the mucosal layer were thickened and atrophied, and round tumor cells had infiltrated the intestinal epithelial cells, crypt epithelial cells and lamina propria. Immunohistochemically, the neoplastic cells were immunoreactive to CD3. Based on these results, the intestinal mass from jejunum was diagnosed as epitheliotropic intestinal T-cell lymphoma.

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Publication Details

Journal
Korean Journal of Veterinary Research
Published
2025-12-31
DOI
https://doi.org/10.14405/kjvr.20250034
Primary Topic
Veterinary Oncology Research
Type
article
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article

Intestinal epitheliotropic T-cell lymphoma in a dog: a case report

Na-Young Lee, Gye-Hyeong Woo, Jae-Hoon Kim, Dae-Yong Kim
Korean Journal of Veterinary Research
Veterinary Oncology Research
article

Intestinal epitheliotropic T-cell lymphoma in a dog: a case report

Na-Young Lee, Gye-Hyeong Woo, Jae-Hoon Kim, Dae-Yong Kim
article en

Abstract

A 13-year-old neutered male Shih Tzu presented with diffuse intestinal thickening extending from the lower part of the duodenum to the middle part of the jejunum. A portion of the jejunum was biopsied and submitted for histopathological diagnosis. Microscopically, the villi of the mucosal layer were thickened and atrophied, and round tumor cells had infiltrated the intestinal epithelial cells, crypt epithelial cells and lamina propria. Immunohistochemically, the neoplastic cells were immunoreactive to CD3. Based on these results, the intestinal mass from jejunum was diagnosed as epitheliotropic intestinal T-cell lymphoma.

Korean Journal of Veterinary ResearchVol. 65(4)
Openalex Percentile: Top 27%
Veterinary Oncology Research
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