Choline kinase α interacts with epidermal growth factor receptor to activate the mitogen-activated protein kinase pathway and contributes to glioma tumorigenesis
CHKA drives glioma malignancy by regulating EGFR and activating the MAPK pathway. The CHKA/EGFR/MAPK axis represents a potential therapeutic target for glioma treatment.
Authors
- Xiao Wu (ORCID: https://orcid.org/0000-0002-9998-8084)
- Hui Ma (ORCID: https://orcid.org/0000-0002-6541-2001)
- Yourui Zou
- Yang Liu
- Yang Zhao
- Haibo Liu
- Peng Gao
- Jin Feng
Institutions
- Ningxia Medical University (CN)
Publication Details
- Journal
- Chinese Medical Journal
- Published
- 2025-12-31
- DOI
- https://doi.org/10.1097/cm9.0000000000003977
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00