Integrating large-scale serum metabolomics and <i>APOE</i> ε4 genotype status for the non-invasive detection of Alzheimer’s disease in the ADNI cohort

Authors

Guillaume Sacco (ORCID: https://orcid.org/0000-0002-6881-1649)
Dany Mukesha (ORCID: https://orcid.org/0009-0001-9514-751X)
Hüseyin Firat

Institutions

Centre National de la Recherche Scientifique (FR)
Inserm (FR)
Centre Hospitalier Universitaire de Nice (FR)
Firalis (France) (FR)
Institut de Recherche sur le Cancer et le Vieillissement de Nice (FR)

Publication Details

Journal: medRxiv
Published: 2025-12-30
DOI: https://doi.org/10.64898/2025.12.29.25343146
Primary Topic: Metabolomics and Mass Spectrometry Studies
Type: article
Field-Weighted Citation Impact: 0.00

Funders

U.S. Department of Defense
Alzheimer's Association
Bristol-Myers Squibb
Eli Lilly and Company
Pfizer
Biogen
Meso Scale Diagnostics
Alzheimer's Disease Neuroimaging Initiative
BioClinica
Novartis Pharmaceuticals Corporation
Eisai
Servier
H. Lundbeck A/S
IXICO
National Institutes of Health
Genentech
Canadian Institutes of Health Research
National Institute on Aging
National Institute of Biomedical Imaging and Bioengineering

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article

Integrating large-scale serum metabolomics and APOE ε4 genotype status for the non-invasive detection of Alzheimer’s disease in the ADNI cohort

Guillaume Sacco, Dany Mukesha, Hüseyin Firat

Dec 30, 2025

medRxiv

Metabolomics and Mass Spectrometry Studies

article

Integrating large-scale serum metabolomics and APOE ε4 genotype status for the non-invasive detection of Alzheimer’s disease in the ADNI cohort

Guillaume Sacco, Dany Mukesha, Hüseyin Firat

December 30, 2025article en

Abstract

No abstract available for this paper.

medRxiv

Centre National de la Recherche Scientifique (FR), Inserm (FR), Centre Hospitalier Universitaire de Nice (FR), Firalis (France) (FR), Institut de Recherche sur le Cancer et le Vieillissement de Nice (FR)

U.S. Department of Defense, Alzheimer's Association, Bristol-Myers Squibb, Eli Lilly and Company, Pfizer, Biogen, Meso Scale Diagnostics, Alzheimer's Disease Neuroimaging Initiative, BioClinica, Novartis Pharmaceuticals Corporation, Eisai, Servier, H. Lundbeck A/S, IXICO, National Institutes of Health, Genentech, Canadian Institutes of Health Research, National Institute on Aging, National Institute of Biomedical Imaging and Bioengineering

Openalex Percentile: Top 35%

Metabolomics and Mass Spectrometry Studies

DOI Open Access PDF OpenAlex

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