Photobiomodulation Therapy as Adjunct to Scaling and Root Planing for Patients with Type 2 Diabetes Mellitus Complicated by Chronic Periodontitis: A Systematic Review and Meta-Analysis

PBMT adjunctive to SRP significantly improves periodontal indices (PD, CAL), FPG, and hs-CRP in patients with T2DM and CP, with borderline HbA1c reduction and good safety. Subgroup analyses identify 808/810 nm + 0.8-1.5 W as potentially optimal PBMT parameters, though high-power efficacy relies on one small-sample study. Given high inter-study heterogeneity (most <i>I</i>² > 90%) and short follow-up (maximum 6 months), conclusions require validation by standardized, large-sample, long-term, high-quality RCTs.