Real-World Indirect Treatment Comparison of Terlipressin vs Midodrine Plus Octreotide in Hepatorenal Syndrome-Acute Kidney Injury

HRS-AKI treatment and outcomes differ between the United Kingdom and the United States, attributed to the historical standard of care MO in the United States. In adjusted analyses, real-world use of terlipressin was more effective than MO at improving kidney function and achieving HRS-AKI reversal.

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Publication Details

Journal
Clinical and Translational Gastroenterology
Published
2025-11-20
DOI
https://doi.org/10.14309/ctg.0000000000000951
Primary Topic
Liver Disease and Transplantation
Type
article
Field-Weighted Citation Impact
0.00
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article

Real-World Indirect Treatment Comparison of Terlipressin vs Midodrine Plus Octreotide in Hepatorenal Syndrome-Acute Kidney Injury

Xingyue Huang, Stevan A. Gonzalez, Douglas A. Simonetto, Viktor Chirikov et al.
Clinical and Translational Gastroenterology
Liver Disease and Transplantation
article

Real-World Indirect Treatment Comparison of Terlipressin vs Midodrine Plus Octreotide in Hepatorenal Syndrome-Acute Kidney Injury

Xingyue Huang, Stevan A. Gonzalez, Douglas A. Simonetto, Viktor Chirikov, Kevin Moore, Andrew S. Allegretti, Wei-Jhih Wang
article en

Abstract

HRS-AKI treatment and outcomes differ between the United Kingdom and the United States, attributed to the historical standard of care MO in the United States. In adjusted analyses, real-world use of terlipressin was more effective than MO at improving kidney function and achieving HRS-AKI reversal.

Clinical and Translational GastroenterologyVol. 17(2)
Open Society Foundations (US), Mayo Clinic (US), The Royal Free Hospital (GB), Massachusetts General Hospital (US), Mallinckrodt (United States) (US), Baylor Scott & White All Saints Medical Center (US), University College London (GB)
Good health and well-being
Openalex Percentile: Top 29%
Liver Disease and Transplantation
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Real-World Indirect Treatment Comparison of Terlipressin vs Midodrine Plus Octreotide in Hepatorenal Syndrome-Acute Kidney Injury — Xingyue Huang, Stevan A. Gonzalez, et al. · Clinical and Translational Gastroenterology (2025) | TGRS Research Map | TGRS