Preventing adjacent segment disease after lumbar fusion: a new perspective emphasizing individualized factors
ASD after PLIF is closely associated with systemic inflammation, lumbar muscle degeneration, cage subsidence, and nonunion. Interventions targeting these risk factors-such as optimizing inflammatory status preoperatively, enhancing lumbar muscle rehabilitation, improving surgical techniques to prevent cage subsidence, and promoting bone fusion-may reduce the incidence of ASD and improve long-term outcomes.
Authors
- Yue Cao (ORCID: https://orcid.org/0000-0002-1434-6366)
- Yusen Qiao
- Zhen Wang (ORCID: https://orcid.org/0000-0001-9289-4889)
- Haifu Sun
- Don Young Park (ORCID: https://orcid.org/0000-0001-9922-3316)
- W. Joyce Tang (ORCID: https://orcid.org/0009-0005-2594-319X)
- Jiafei Ji
- Yoji Ogura
- Junfeng Shi
Institutions
- Nantong University (CN)
- University of California, Irvine (US)
- Soochow University (CN)
- Affiliated Hospital of Nantong University (CN)
- Second Affiliated Hospital of Soochow University (CN)
- Tachikawa Hospital (JP)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- Quantitative Imaging in Medicine and Surgery
- Published
- 2025-12-31
- DOI
- https://doi.org/10.21037/qims-2025-1462
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00