Oridonin Ameliorates Macrophage Oxidative Stress and Pyroptosis In Liver Ischemia–Reperfusion Injury by Inhibiting Mitochondrial ROS/TXNIP/NLRP3
Oridonin effectively protects against LIRI by decreasing macrophage M1 polarization, oxidative stress, and pyroptosis through inhibition of the mitochondrial ROS/TXNIP/NLRP3 pathway.
Authors
- Xinyi Wu
- Wei Liao (ORCID: https://orcid.org/0000-0003-3009-7133)
- Shengwei Li
- Jianping Gong
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Shock
- Published
- 2025-12-30
- DOI
- https://doi.org/10.1097/shk.0000000000002673
- Primary Topic
- Bioactive Natural Diterpenoids Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00