Mucorales PCR Testing in Respiratory and Biopsy Samples From Immunocompromised Patients With Invasive Pulmonary Aspergillosis and Other Mold Infections: Results From a Multicenter ECMM Study
MucorGenius® PCR showed high sensitivity for detecting Mucorales and may support improved diagnosis of probable mucormycosis when included as a mycological criterion. It appears particularly valuable for identifying <i>Aspergillus</i>-Mucorales coinfections and detecting mucormycosis in patients with host factors, clinical or radiological evidence of IMI when routine diagnostics are negative.
Authors
- K. Lagrou
- Jochem B. Buil (ORCID: https://orcid.org/0000-0003-4031-0778)
- Harald H. Kessler (ORCID: https://orcid.org/0000-0002-3015-0398)
- Silke Schelenz (ORCID: https://orcid.org/0000-0002-0108-4619)
- Raquel Posso
- Karl Dichtl (ORCID: https://orcid.org/0000-0001-5032-8870)
- Yuri Vanbiervliet (ORCID: https://orcid.org/0000-0002-6169-1920)
- Martin Hoenigl (ORCID: https://orcid.org/0000-0002-1653-2824)
- Robina Aerts (ORCID: https://orcid.org/0000-0001-6337-6636)
- Alireza Abdolrasouli (ORCID: https://orcid.org/0000-0002-8934-2343)
- Sarah Sedik (ORCID: https://orcid.org/0009-0002-3070-2508)
- Johan Maertens
- Lewis White
- Juergen Prattes
Institutions
- Radboud University Nijmegen (NL)
- Medical University of Graz (AT)
- Rega Institute for Medical Research (BE)
- University Hospital of Wales (GB)
- University Medical Center (US)
- Radboud University Medical Center (NL)
- Radboud Institute for Molecular Life Sciences (NL)
- King's College Hospital (GB)
- KU Leuven (BE)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2025-12-25
- DOI
- https://doi.org/10.1093/ofid/ofaf801
- Citations
- 2
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 2.79