The role of aetiology in determining anticoagulation effectiveness for the treatment of left ventricular thrombus
The underlying aetiology of LV dysfunction significantly influences both treatment response and outcomes in patients with LV thrombus. Direct oral anticoagulant were associated with superior efficacy and safety in AMI-related LV thrombus, but were linked to increased rates of SSE in NICM. These findings highlight the importance of aetiology on LV thrombus management and the potential need for tailored approaches.
Authors
- P Wright
- Krishnaraj Sinhji Rathod (ORCID: https://orcid.org/0000-0003-4268-5055)
- Robert O’Dowling
- Holly Morgan (ORCID: https://orcid.org/0000-0002-6636-6174)
- Amedeo Chiribiri (ORCID: https://orcid.org/0000-0003-3394-4289)
- Andrew Wragg (ORCID: https://orcid.org/0000-0002-8934-5712)
- Daniel A. Jones (ORCID: https://orcid.org/0000-0003-1441-0417)
- Anthony Mathur (ORCID: https://orcid.org/0000-0001-7941-9653)
- S Antoniou
- Divaka Perera
- Bianca Maria Coldea (ORCID: https://orcid.org/0009-0009-8193-8693)
- Christopher Pieri
- Benjamin Waters
- Johanna Jones
Institutions
- Queen Mary University of London (GB)
- Barts Health NHS Trust (GB)
- St. Thomas Hospital (CA)
- William Harvey Research Institute (GB)
Publication Details
- Journal
- European Heart Journal - Cardiovascular Pharmacotherapy
- Published
- 2025-12-31
- DOI
- https://doi.org/10.1093/ehjcvp/pvaf091
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00