Population‐Based Case–Control Study of Antidepressants in Early and Average‐Age Onset Colorectal Cancer: The Impact of Exposure Window, Class, Dose, and Intensity
Across all age groups, antidepressant exposure in the earlier exposure windows (15-7 years) was associated with a lower CRC risk, with the strongest effect at the 15-year window.
Authors
- Vicki Cheng (ORCID: https://orcid.org/0000-0001-5030-9135)
- Mary A. De Vera (ORCID: https://orcid.org/0000-0002-2205-2683)
- Eric C. Sayre (ORCID: https://orcid.org/0000-0002-4526-278X)
- Rachel A. Murphy (ORCID: https://orcid.org/0000-0003-4383-5641)
- Jonathan Loree
- Vienna Cheng (ORCID: https://orcid.org/0009-0009-7053-559X)
- Sharlene Gill
Institutions
- University of British Columbia (CA)
- British Columbia Centre on Substance Use (CA)
- Centre for Advancing Health Outcomes (CA)
- Canadian Centre for Applied Research in Cancer Control (CA)
Publication Details
- Journal
- Pharmacoepidemiology and Drug Safety
- Published
- 2025-12-30
- DOI
- https://doi.org/10.1002/pds.70316
- Primary Topic
- Cancer, Stress, Anesthesia, and Immune Response
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Canadian Institutes of Health Research