The Evolution in the Cutaneous and Gastrointestinal Pathology of Pediatric Kohlmeier–Degos Disease Under Combined Modality Therapy
The cutaneous and extracutaneous lesions of Kohlmeier-Degos disease are potentially reversible. The combination of therapeutic complement inhibition, downregulation of type I interferon expression, and the promotion of vascular patency and reduced platelet activation through prostacyclin administration define the cornerstone of treatment.
Authors
- Lee Shapiro (ORCID: https://orcid.org/0000-0002-6652-3141)
- CYNTHIA M.J. MAGRO (ORCID: https://orcid.org/0000-0003-2099-2636)
- Elizabeth A. Kessler
- Katherine Foster
Institutions
- Cornell University (US)
- Helen DeVos Children's Hospital (US)
- Weill Cornell Medicine (US)
- Albany Medical Center Hospital (US)
Publication Details
- Journal
- American Journal of Dermatopathology
- Published
- 2025-12-31
- DOI
- https://doi.org/10.1097/dad.0000000000003193
- Primary Topic
- Parvovirus B19 Infection Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00