Implantable artificial lymph node enables rapid in vivo neoantigen-specific T-cell generation and expansion for improving antitumor immunity
Our results demonstrate that implantable FAST-LN rapidly induces tumor neoantigen-specific T cells in vivo, offering a promising strategy for neoantigen-based cancer immunotherapy.
Authors
- P.K. Chen
- Yongyi Zeng (ORCID: https://orcid.org/0000-0001-7441-4271)
- Junjing Huang (ORCID: https://orcid.org/0000-0001-6352-3472)
- Xiuqing Dong
- Lin Kongying
- Zhenli Li (ORCID: https://orcid.org/0000-0002-3997-2187)
- Luobin Guo
- Pan Mou
- Zhixiong Cai
- Geng Chen
- Ling Li
- Ruijing Tang
- Xiaolong Liu
Institutions
- Fujian Medical University (CN)
- Mengchao Hepatobiliary Hospital (CN)
Publication Details
- Journal
- Journal for ImmunoTherapy of Cancer
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1136/jitc-2025-013043
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00