Establishing National Guidance for Idiopathic Granulomatous Mastitis (ENIGMA): a scoping review of diagnostic practice

Substantial heterogeneity exists in the diagnostic workup for IGM, particularly in excluding infectious and systemic causes. Histopathology alone is insufficient for definitive diagnosis. A comprehensive, standardised diagnostic framework that incorporates clinical, microbiological and epidemiological factors is needed to improve diagnostic accuracy and ensure appropriate management, particularly in the context of possible immunosuppressive therapy.

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Publication Details

Journal
Journal of Clinical Pathology
Published
2025-12-30
DOI
https://doi.org/10.1136/jcp-2025-210394
Primary Topic
Breast Lesions and Carcinomas
Type
article
Field-Weighted Citation Impact
0.00
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article

Establishing National Guidance for Idiopathic Granulomatous Mastitis (ENIGMA): a scoping review of diagnostic practice

Roisin Bradley, Rute Castelhano, Karina Cox, Rudresh Shukla et al.
Journal of Clinical Pathology
Breast Lesions and Carcinomas
article

Establishing National Guidance for Idiopathic Granulomatous Mastitis (ENIGMA): a scoping review of diagnostic practice

Roisin Bradley, Rute Castelhano, Karina Cox, Rudresh Shukla, Christopher Darlow, Cliona Kirwan, Leah Argus, Goonj Johri, Nisha Sharma, Vijay K Sharma, Kavita Sethi, Daniel Ahari, Shaneel Shah, Emma McInnnes, Iain Lyburn
article en

Abstract

Substantial heterogeneity exists in the diagnostic workup for IGM, particularly in excluding infectious and systemic causes. Histopathology alone is insufficient for definitive diagnosis. A comprehensive, standardised diagnostic framework that incorporates clinical, microbiological and epidemiological factors is needed to improve diagnostic accuracy and ensure appropriate management, particularly in the context of possible immunosuppressive therapy.

Journal of Clinical PathologyVol. 79(4)
University of Liverpool (GB), Guy's and St Thomas' NHS Foundation Trust (GB), Aintree University Hospitals NHS Foundation Trust (GB), Leeds Teaching Hospitals NHS Trust (GB), Manchester Academic Health Science Centre (GB), Gloucestershire Hospitals NHS Foundation Trust (GB), University Hospital Southampton NHS Foundation Trust (GB), University of Manchester (GB), Manchester University NHS Foundation Trust (GB), Cobalt Institute (GB), York Teaching Hospital NHS Foundation Trust (GB), Cancer Research UK Manchester Institute (GB), NIHR Manchester Biomedical Research Centre (GB)
Reduced inequalities
Openalex Percentile: Top 28%
Breast Lesions and Carcinomas
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