Hypothyroidism is Associated with Higher Fatty Infiltration in Multifidus and Erector Spinae Muscles in Lumbar Spinal Stenosis

Hypothyroidism and female sex are associated with increased fatty degeneration of paraspinal muscles in LSS. Elevated T4 levels may reflect treatment status rather than endogenous overproduction. ESP infiltration may serve as a radiographic marker of hypothyroidism and aid in preoperative evaluation and risk stratification.

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Publication Details

Journal
World Neurosurgery
Published
2025-12-31
DOI
https://doi.org/10.1016/j.wneu.2025.124781
Primary Topic
Spine and Intervertebral Disc Pathology
Type
article
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article

Hypothyroidism is Associated with Higher Fatty Infiltration in Multifidus and Erector Spinae Muscles in Lumbar Spinal Stenosis

Omar S. Akbik, Salah Ghassan Aoun, Milan Sivakumar, Carlos A. Bagley et al.
World Neurosurgery
Spine and Intervertebral Disc Pathology
article

Hypothyroidism is Associated with Higher Fatty Infiltration in Multifidus and Erector Spinae Muscles in Lumbar Spinal Stenosis

Omar S. Akbik, Salah Ghassan Aoun, Milan Sivakumar, Carlos A. Bagley, Nina Dwarfour Poku, Sruthi Ranganthan, Sean O’Leary, Dhillon Advano, Sahil Chilukuri, Srivats Srinivasan, Mina Guirguis
article en

Abstract

Hypothyroidism and female sex are associated with increased fatty degeneration of paraspinal muscles in LSS. Elevated T4 levels may reflect treatment status rather than endogenous overproduction. ESP infiltration may serve as a radiographic marker of hypothyroidism and aid in preoperative evaluation and risk stratification.

World NeurosurgeryVol. 206
University of Cambridge (GB), CHI Health Creighton University Medical Center - Bergan Mercy (US), Southwestern Medical Center (US), Neurological Surgery (US), The University of Texas Medical Branch at Galveston (US), Albany Medical Center Hospital (US), The University of Texas Southwestern Medical Center (US)
Gender equality
Openalex Percentile: Top 28%
Spine and Intervertebral Disc Pathology
DOIOpen Access PDFOpenAlex
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Hypothyroidism is Associated with Higher Fatty Infiltration in Multifidus and Erector Spinae Muscles in Lumbar Spinal Stenosis — Omar S. Akbik, Salah Ghassan Aoun, et al. · World Neurosurgery (2025) | TGRS Research Map | TGRS