NAD+-mediated SIRT1–LKB1–AMPK signaling drives lipid remodeling and meat quality differences between Daweishan miniature and Arbor Acres chicken breeds
These results indicate that M1 chickens exhibit enhanced metabolic regulation and protein-rich muscle with distinct lipid remodeling, whereas A1 broilers favor rapid growth and fat accumulation. The study provides mechanistic insight into breed-specific differences in muscle metabolism and meat quality, highlighting NAD<sup>+</sup> and its signaling axis as key regulators of lipid homeostasis in chicken breast muscle.
Authors
- Jingying Zhao
- Zhiqiang Xu
- Jing Fu
- Shixiong Yan
- Tengfei Dou
- Hao Wu
- Lixian Liu
- Zonghui Jian
- Junjing Jia
- Junfeng Luo
- Min Yang
Institutions
- Yunnan Agricultural University (CN)
- Yunnan Animal Science and Veterinary Institute (CN)
- Yunnan Forestry Vocational and Technical College (CN)
- Chuxiong Normal University (CN)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2025-12-31
- DOI
- https://doi.org/10.3389/fvets.2025.1711416
- Primary Topic
- Sirtuins and Resveratrol in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China