Cryoablation combined with chemotherapy for the treatment of liver metastases

Cryoablation-chemotherapy combination treatment is safe, feasible, and effective for LMs. Its efficacy is mainly dependent on the primary tumor site, making it a potential alternative for clinical treatments. CLMs had better prognosis than NCLMs. A maximum tumor diameter ≥3 cm, time to LMs ≤12 months, and absence of neoadjuvant TACE were identified as statistically significant predictors of poor prognosis in patients with LM.