Association of GLP-1 receptor agonists with herpes risks in diabetes mellitus: a target trial emulation

GLP-1RA use is associated with an increased risk of HSV and HZ infections compared with SGLT-2i or a DPP-4i use, especially in younger, female, and poorly controlled T2DM patients. Vaccination against herpes zoster is essential in mitigating these risks.

Authors

Institutions

Publication Details

Journal
BMC Medicine
Published
2025-12-31
DOI
https://doi.org/10.1186/s12916-025-04606-w
Primary Topic
Herpesvirus Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Association of GLP-1 receptor agonists with herpes risks in diabetes mellitus: a target trial emulation

I. L. Liu, I-Hui Chiang, Huang Jing-yang, I-Cheng Lu et al.
BMC Medicine
Herpesvirus Infections and Treatments
article

Association of GLP-1 receptor agonists with herpes risks in diabetes mellitus: a target trial emulation

I. L. Liu, I-Hui Chiang, Huang Jing-yang, I-Cheng Lu, James Cheng-Chung Wei, Pei-Lun Liao, Po-Husan Lai, Chi-Wei Lin, Ming-Ta Hsieh, Chi-Hsien Huang
article en

Abstract

GLP-1RA use is associated with an increased risk of HSV and HZ infections compared with SGLT-2i or a DPP-4i use, especially in younger, female, and poorly controlled T2DM patients. Vaccination against herpes zoster is essential in mitigating these risks.

BMC MedicineVol. 24(1)
Asia University (TW), Kaohsiung Medical University (TW), China Medical University (TW), E-Da Hospital (TW), Chung Shan Medical University Hospital (TW), Chung Shan Medical University (TW), I-Shou University (TW)
Good health and well-being
Openalex Percentile: Top 29%
Herpesvirus Infections and Treatments
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Association of GLP-1 receptor agonists with herpes risks in diabetes mellitus: a target trial emulation — I. L. Liu, I-Hui Chiang, et al. · BMC Medicine (2025) | TGRS Research Map | TGRS