Baishaoluoshi Decoction Mitigates Post‐Stroke Spasticity by Targeting Synaptic Plasticity Through the Nogo‐A/NgR Signaling Pathway
BD alleviates PSS by enhancing synaptic plasticity and suppressing inhibitory signaling through multitarget modulation of neuron-glia interactions. These findings highlight BD as a promising therapeutic intervention for PSS, which is supported by molecular evidence of its effects on synaptic remodeling and functional recovery.
Authors
- Shigao Lin
- Lu Li (ORCID: https://orcid.org/0000-0002-9398-4488)
- Yuhui Zhang (ORCID: https://orcid.org/0000-0002-5158-0645)
- Xiongxing Sun
- Xukun Tang
- L. Wu
- Shanshan Zeng (ORCID: https://orcid.org/0000-0003-0647-7953)
- Dahua Wu
- Ziming Chen
- Jiajian Zhu
- Le Xie
- Xinyu Deng
Institutions
- Hunan University of Traditional Chinese Medicine (CN)
- Hunan Academy of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-12-31
- DOI
- https://doi.org/10.1002/brb3.71170
- Primary Topic
- Axon Guidance and Neuronal Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Hunan University
- Hunan University of Chinese Medicine