Selegiline Improved Oxidative and Inflammatory Stress Factors in Gentamicin-Induced Nephrotoxicity in Human Renal Tubular Epithelial Cells

These findings show that selegiline can have protective effects on kidney damage caused by gentamicin and by reducing oxidative stress and inflammation, it can be proposed as a promising treatment option to reduce the side effects of gentamicin.

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Publication Details

Journal
International Journal of Preventive Medicine
Published
2025-12-01
DOI
https://doi.org/10.4103/ijpvm.ijpvm_361_24
Primary Topic
Antibiotics Pharmacokinetics and Efficacy
Type
article
Field-Weighted Citation Impact
0.00
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article

Selegiline Improved Oxidative and Inflammatory Stress Factors in Gentamicin-Induced Nephrotoxicity in Human Renal Tubular Epithelial Cells

Khojasteh Hoseinynejad, Fereshteh Nejaddehbashi, Mahsa Poursangbor, Maryam Radan
International Journal of Preventive Medicine
Antibiotics Pharmacokinetics and Efficacy
article

Selegiline Improved Oxidative and Inflammatory Stress Factors in Gentamicin-Induced Nephrotoxicity in Human Renal Tubular Epithelial Cells

Khojasteh Hoseinynejad, Fereshteh Nejaddehbashi, Mahsa Poursangbor, Maryam Radan
article en

Abstract

These findings show that selegiline can have protective effects on kidney damage caused by gentamicin and by reducing oxidative stress and inflammation, it can be proposed as a promising treatment option to reduce the side effects of gentamicin.

International Journal of Preventive MedicineVol. 16
Ahvaz Jundishapur University of Medical Sciences (IR)
Openalex Percentile: Top 29%
Antibiotics Pharmacokinetics and Efficacy
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