Eupatorin as a Promising Natural Compound Against Knee Osteoarthritis: From Network Pharmacology to Experimental Validation

Eupatorin has demonstrated potential for use in KOA therapy by targeting inflammation and ECM, and by regulating the PI3K/AKT and estrogen-associated signaling pathways.

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Publication Details

Journal
Frontiers in Bioscience-Landmark
Published
2025-12-22
DOI
https://doi.org/10.31083/fbl46747
Primary Topic
Osteoarthritis Treatment and Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Eupatorin as a Promising Natural Compound Against Knee Osteoarthritis: From Network Pharmacology to Experimental Validation

Jifu Du, Meixia Zhao, Ting-Ting null Meng, Chun-Meng null Huang et al.
Frontiers in Bioscience-Landmark
Osteoarthritis Treatment and Mechanisms
article

Eupatorin as a Promising Natural Compound Against Knee Osteoarthritis: From Network Pharmacology to Experimental Validation

Jifu Du, Meixia Zhao, Ting-Ting null Meng, Chun-Meng null Huang, Yang-Shuo null Ge, Dao-Fang null Ding, Liao-Lin null Chen, Xu-Bo null Wu, Jia-Hui null Luo, Yu-Qing null Zhai, Xin-Hui null Huang, Jian-Li null Yin
article en

Abstract

Eupatorin has demonstrated potential for use in KOA therapy by targeting inflammation and ECM, and by regulating the PI3K/AKT and estrogen-associated signaling pathways.

Frontiers in Bioscience-LandmarkVol. 30(12)
Shanghai University of Traditional Chinese Medicine (CN), Shanghai Second People's Hospital (CN), Shanghai Institute of Applied Physics (CN), Pudong New Area People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 26%
Osteoarthritis Treatment and Mechanisms
DOIOpen Access PDFOpenAlex
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Eupatorin as a Promising Natural Compound Against Knee Osteoarthritis: From Network Pharmacology to Experimental Validation — Jifu Du, Meixia Zhao, et al. · Frontiers in Bioscience-Landmark (2025) | TGRS Research Map | TGRS