Duodenal metastases from lung adenocarcinoma causing gastrointestinal bleeding: a rare aetiology

Gastrointestinal metastases from primary lung adenocarcinoma are rare, with only a few reported cases of gastrointestinal bleeding caused by such metastases. Among the cancers that most commonly spread to the gastrointestinal tract are lung, breast, kidney and melanoma. Symptoms can vary, but patients are usually asymptomatic, presenting in advanced stages. We present a case of gastrointestinal bleeding secondary to a duodenal ulcer found to be a metastatic lesion from primary lung adenocarcinoma. Although the diagnosis can be challenging, especially when no lung malignancy is known yet, immunochemistry can be used to differentiate between primary gastrointestinal cancer and lung cancer metastasis.

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Publication Details

Journal
BMJ Case Reports
Published
2025-12-01
DOI
https://doi.org/10.1136/bcr-2025-266682
Primary Topic
Metastasis and carcinoma case studies
Type
article
Field-Weighted Citation Impact
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article

Duodenal metastases from lung adenocarcinoma causing gastrointestinal bleeding: a rare aetiology

Nedda Rahim, Asim Shuja, Snehal Sonawane, Gabriela Mendez
BMJ Case Reports
Metastasis and carcinoma case studies
article

Duodenal metastases from lung adenocarcinoma causing gastrointestinal bleeding: a rare aetiology

Nedda Rahim, Asim Shuja, Snehal Sonawane, Gabriela Mendez
article en

Abstract

Gastrointestinal metastases from primary lung adenocarcinoma are rare, with only a few reported cases of gastrointestinal bleeding caused by such metastases. Among the cancers that most commonly spread to the gastrointestinal tract are lung, breast, kidney and melanoma. Symptoms can vary, but patients are usually asymptomatic, presenting in advanced stages. We present a case of gastrointestinal bleeding secondary to a duodenal ulcer found to be a metastatic lesion from primary lung adenocarcinoma. Although the diagnosis can be challenging, especially when no lung malignancy is known yet, immunochemistry can be used to differentiate between primary gastrointestinal cancer and lung cancer metastasis.

BMJ Case ReportsVol. 18(12)
Khyber Medical University (PK), University of Illinois Chicago (US)
Good health and well-being
Openalex Percentile: Top 27%
Metastasis and carcinoma case studies
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Duodenal metastases from lung adenocarcinoma causing gastrointestinal bleeding: a rare aetiology — Nedda Rahim, Asim Shuja, et al. · BMJ Case Reports (2025) | TGRS Research Map | TGRS