Lnc-ANRIL Protects Against Myocardial Ischemia-Reperfusion Injury by Suppressing Ferroptosis via the miR-7238-3p/GPX4 Axis
MI/RI downregulates lnc-ANRIL, relieving inhibition of miR-7238-3p and suppressing GPX4, thereby triggering ferroptosis in cardiomyocytes. Lnc-ANRIL protects against MI/RI-induced ferroptosis via the miR-7238-3p/GPX4 axis, suggesting a potential therapeutic target.
Authors
- Jian Mo (ORCID: https://orcid.org/0000-0002-2084-8450)
- Binhua Wu
- Guixi Mo
- Yijun Liu
- Kui Hu
Institutions
- Guangdong Medical College (CN)
- Zhanjiang Experimental Station (CN)
- Affiliated Hospital of Guangdong Medical College Hospital (CN)
- First Affiliated Hospital of Jinan University (CN)
Publication Details
- Journal
- Cellular Physiology and Biochemistry
- Published
- 2025-12-31
- DOI
- https://doi.org/10.33594/000000837
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science and Technology Planning Project of Guangdong Province