First-in-Human Study of 68Ga-FAP-75 PET Imaging of Cancer-associated Fibroblasts
The novel FAP-targeted probe 68 Ga-FAP-75 exhibits favorable biodistribution, pharmacokinetics, and safety, with good tumor specificity and a favorable tumor-to-background ratio, showing great potential in tumor imaging and radionuclide-targeted therapy.
Authors
- Chunxia Qin
- Xiaoli Lan
- YuHu Lv
- Yuchen Jin (ORCID: https://orcid.org/0000-0001-9781-8682)
- Mengting Li
- Yongkang Gai
- Huan Wang
- Yuanyuan Huang
- Fan Hu
- Feihu Guo
- Yun Zhang
Institutions
- Active Medicine (United Kingdom) (GB)
- Ministry of Education (CL)
- Jiangsu Hengrui Medicine (China) (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Clinical Nuclear Medicine
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1097/rlu.0000000000006157
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00