Diagnostic accuracy of self-collected anterior nasal swabs for SARS-CoV-2 RT-PCR testing
In this study, we compared the PCR results of self-collected anterior nasal swabs against healthcare professional-collected combined throat and nasal swabs. The sensitivity and specificity of the anterior nasal swab were considered acceptable when compared to World Health Organization recommendations. The sensitivity of the Rhinoswab ANS was higher at the beginning of the trial when compared with the final day of the trial, regardless of the number of prongs tested via PCR. The self-collected Rhinoswab is a valid tool for community screening of severe acute respiratory syndrome coronavirus 2 in vulnerable populations.
Authors
- Natasha Letunica (ORCID: https://orcid.org/0000-0003-3604-1536)
- Craig Aboltins (ORCID: https://orcid.org/0000-0002-7578-882X)
- G. E. Anderson
- Prahlad Ho (ORCID: https://orcid.org/0000-0003-1875-3927)
- Shidan Tosif (ORCID: https://orcid.org/0000-0003-0022-1009)
- Kerry Fitzmaurice
- Chantal Attard (ORCID: https://orcid.org/0000-0002-4428-1663)
- Tayla‐Ann Corocher (ORCID: https://orcid.org/0000-0003-1127-0500)
- Sarosh Sadiq (ORCID: https://orcid.org/0000-0003-4634-6982)
- Sue Lynn. Lim
- Pei-Yu Ho
- Gopika Krishnamurthy
- Kathryn M. Edwards (ORCID: https://orcid.org/0000-0003-3912-9832)
- Seraphina Kwak
- Donald Campbell (ORCID: https://orcid.org/0009-0006-2639-7001)
- Lucy Hanlon (ORCID: https://orcid.org/0000-0002-8648-6165)
- Susan Russel
- Paul Monagle (ORCID: https://orcid.org/0000-0002-3970-8984)
- Vasiliki Karlaftis (ORCID: https://orcid.org/0000-0002-1443-2352)
- Vera Ignjatović (ORCID: https://orcid.org/0000-0002-5548-5813)
- Yuqi Mao
- Mark Crowther (ORCID: https://orcid.org/0000-0003-4986-4873)
- Jesica Oktaviana
- Yvonne Hersusianto
- Şeyma Nur Mülayim
- Suguna Ganesan
- Kira Edwards
- D. Campbell
- Anneke Grobler
- Abeerah Sadiq
- Jessica Josephine Edwards
- Sharon Tay
- Madonna Sanchez
- Blazhenka-Angelika Gjorgjevska
- Noel Cranswick
- Marion Angelika Kainer
- Christopher Dong
- Hui Yin Lim
- Fiona Newall
- Andrew Davidson
- Tanya Anand
- Avanthika Lakshmanan
- Nivein Yenis
- Kit Yee Tang
- Jodi Hislop
- Rizelle Santos
- Taylor Corocher
- Elise Simonato
- the INHERIT Trial Group
- Jingnan Lisa Zhang
- Joe Toressi
- Loren Sher
- Amelia Maria Sfameni
- Sophie May Roberts
- Derwin Or
- Thomas Sullivan
- Vinod Chellaram
- Tissa Wijeratne
- Steven Y.C. Tong
- Timothy Hinks
- Henry Wong
- Valerie Yee
- Alexandra Brown
- Matthew Alexander Murphy
- Meredith Wiggins
- Jier Nguyen
- Hui Bing Ooi
- Damian Purcell
- Michelle McIntosh
- Barry Dixon
- Philip Vukovic
- Huyen Tran
- Jan Trisha Sanchez
- Laura Fangqi Chen
Institutions
- Royal Children's Hospital (AU)
- The University of Melbourne (AU)
- Northern Health (AU)
- Sydney Children's Hospital (AU)
- Australian Centre for HIV and Hepatitis Virology Research (AU)
- Murdoch Children's Research Institute (AU)
- Monash University (AU)
Publication Details
- Journal
- Microbiology Spectrum
- Published
- 2025-12-31
- DOI
- https://doi.org/10.1128/spectrum.01711-25
- Primary Topic
- SARS-CoV-2 detection and testing
- Type
- article
- Field-Weighted Citation Impact
- 0.00