Hypochlorous Acid as an Adjunctive Treatment for Periocular Necrotizing Fasciitis

The authors describe a simple method of introducing dilute, pure HOCL (0.033%) without hypochlorite or sodium hypochlorite as impurities via irrigation and topical spray into the treatment plan for PONF. There was little if any loss of tissue with this treatment in this series. The outcomes compared favorably to those outcomes in the literature of PONF patients treated more traditionally with antibiotics and debridement, and those patients treated more conservatively with antibiotics alone. HOCL irrigation and spray techniques appear to be beneficial in the management of PONF and decrease the need to debride, allowing faster disease resolution and contributing to favorable outcomes.

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Publication Details

Journal
Ophthalmic Plastic and Reconstructive Surgery
Published
2025-12-31
DOI
https://doi.org/10.1097/iop.0000000000003170
Primary Topic
Otolaryngology and Infectious Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Hypochlorous Acid as an Adjunctive Treatment for Periocular Necrotizing Fasciitis

D R Jordan, Pushpinder Kanda
Ophthalmic Plastic and Reconstructive Surgery
Otolaryngology and Infectious Diseases
article

Hypochlorous Acid as an Adjunctive Treatment for Periocular Necrotizing Fasciitis

D R Jordan, Pushpinder Kanda
article en

Abstract

The authors describe a simple method of introducing dilute, pure HOCL (0.033%) without hypochlorite or sodium hypochlorite as impurities via irrigation and topical spray into the treatment plan for PONF. There was little if any loss of tissue with this treatment in this series. The outcomes compared favorably to those outcomes in the literature of PONF patients treated more traditionally with antibiotics and debridement, and those patients treated more conservatively with antibiotics alone. HOCL irrigation and spray techniques appear to be beneficial in the management of PONF and decrease the need to debride, allowing faster disease resolution and contributing to favorable outcomes.

Ophthalmic Plastic and Reconstructive Surgery
University of Ottawa (CA)
Openalex Percentile: Top 30%
Otolaryngology and Infectious Diseases
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