Minimally invasive vs. trans-sternal thymectomy for non-thymomatous myasthenia gravis: a multi-institutional longitudinal study examining neurologic outcomes

Our study confirms the results of the landmark MGTX (Randomized Trial of Thymectomy in Myasthenia Gravis) trial in a real-world multicenter experience. Similar outcomes were achieved regardless of surgical approach. These data support thymectomy for MG either by a minimally invasive or trans-sternal approach. This is the first study to compare disease-specific, rather than perioperative, outcomes of thymectomy via sternotomy <i>vs.</i> minimally invasive approach.

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Publication Details

Journal
Journal of Thoracic Disease
Published
2025-12-01
DOI
https://doi.org/10.21037/jtd-24-423
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
Field-Weighted Citation Impact
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article

Minimally invasive vs. trans-sternal thymectomy for non-thymomatous myasthenia gravis: a multi-institutional longitudinal study examining neurologic outcomes

Joseph D. Phillips, Joshua A. Boys, Linda W. Martin, Betül Gündoğdu et al.
Journal of Thoracic Disease
Myasthenia Gravis and Thymoma
article

Minimally invasive vs. trans-sternal thymectomy for non-thymomatous myasthenia gravis: a multi-institutional longitudinal study examining neurologic outcomes

Joseph D. Phillips, Joshua A. Boys, Linda W. Martin, Betül Gündoğdu, Rachel Williams, Peter Tatum, Matthew Elliot, Kayla A. Fay, Dustin M. Walters, J. Hunter Mehaffey, Ryan Hall, Jared P. Beller
article en

Abstract

Our study confirms the results of the landmark MGTX (Randomized Trial of Thymectomy in Myasthenia Gravis) trial in a real-world multicenter experience. Similar outcomes were achieved regardless of surgical approach. These data support thymectomy for MG either by a minimally invasive or trans-sternal approach. This is the first study to compare disease-specific, rather than perioperative, outcomes of thymectomy via sternotomy <i>vs.</i> minimally invasive approach.

Journal of Thoracic DiseaseVol. 17(12)
Tufts University (US), University of Connecticut (US), University of Virginia Health System (US), University of California San Diego (US), UConn Health (US)
Openalex Percentile: Top 30%
Myasthenia Gravis and Thymoma
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Minimally invasive vs. trans-sternal thymectomy for non-thymomatous myasthenia gravis: a multi-institutional longitudinal study examining neurologic outcomes — Joseph D. Phillips, Joshua A. Boys, et al. · Journal of Thoracic Disease (2025) | TGRS Research Map | TGRS