Patient Satisfaction after Radiofrequency Ablation of Benign Thyroid Nodules: A Comparative Analysis Based on Nodule Type and Volume

Background — The incidence of thyroid nodules is increasing. Although most are benign and asymptomatic, some require treatment for compressive or cosmetic reasons. Radiofrequency ablation (RFA) is a minimally invasive alternative to surgery. To date, published studies focused on the technical aspects of RFA, while comparative analysis of patient satisfaction depending on nodule volume was limited. Methods — This prospective cohort study analyzed 101 patients who underwent RFA for benign thyroid nodules (from January 9, 2019, to October 15, 2024). Patients were distributed among two groups depending on nodule volume (<10 ml and ≥10 ml). Post-procedural satisfaction was assessed using questionnaires regarding physical and emotional well-being. Results — We observed high overall patient satisfaction. Although nodule volume did not significantly affect overall satisfaction, larger nodules were associated with higher rates of a full symptomatic satisfaction. Satisfaction with cosmetic outcome was similar across nodule volume groups. Significant volume reduction was observed at 24 months of follow-up. Conclusion — RFA results in high patient satisfaction for benign thyroid nodules. Nodule size influences several aspects of the experience, highlighting the need for further research examining factors affecting patient satisfaction beyond nodule volume.