Multi-Modal Profiling Reveals SERPINB3-Driven Immune Evasion and Stromal Immune Mimicry in Triple-Negative Breast Cancer

Together, these data indicate that TNBC exhibits co-existing immune activation and immune-suppressive features. The identified epithelial and stromal signatures represent candidate biomarkers that may inform future studies of immune regulation and therapeutic stratification in TNBC.

Authors

Zinab O. Doha (ORCID: https://orcid.org/0000-0003-2952-9840)

Institutions

Taibah University (SA)

Publication Details

Journal: Genes
Published: 2025-12-31
DOI: https://doi.org/10.3390/genes17010038
Primary Topic: Cancer Immunotherapy and Biomarkers
Type: article
Field-Weighted Citation Impact: 0.00

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article

Multi-Modal Profiling Reveals SERPINB3-Driven Immune Evasion and Stromal Immune Mimicry in Triple-Negative Breast Cancer

Zinab O. Doha

Dec 31, 2025

Genes

Cancer Immunotherapy and Biomarkers

article

Multi-Modal Profiling Reveals SERPINB3-Driven Immune Evasion and Stromal Immune Mimicry in Triple-Negative Breast Cancer

Zinab O. Doha

December 31, 2025article en

Abstract

GenesVol. 17(1)

Taibah University (SA)

Good health and well-being

Openalex Percentile: Top 30%

Cancer Immunotherapy and Biomarkers

DOI Open Access PDF OpenAlex

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Multi-Modal Profiling Reveals SERPINB3-Driven Immune Evasion and Stromal Immune Mimicry in Triple-Negative Breast Cancer — Zinab O. Doha · Genes (2025) | TGRS Research Map | TGRS