A Retrospective Study on the Clinicopathological Characteristics and Prognostic Analysis of Gynecologic Neuroendocrine Carcinoma

Cervical NEC was the predominant subtype, most patients underwent surgery with adjuvant therapy, and survival was strongly stage-dependent. MiNEN with squamous cell carcinoma independently predicted worse PFS, highlighting a potential high-risk subgroup and reinforcing the need for multicenter prospective studies and more effective, potentially targeted treatment approaches for gynecologic NECs.